Anxiolytic effect of clonazepam in female rats: Grooming microstructure and elevated plus maze tests
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چکیده
منابع مشابه
Anxiolytic Effect of Ocimum basilicum Extract in Rats Tested by Elevated Plus-Maze Task
Background: There are reports in traditional medicine about the effectiveness of Ocimum basilicum (OB) in the treatment of anxiety. The Elevated Plus-Maze (EPM) has been predominantly used to investigate anxiety levels in rodents. Objectives: The purpose of the present study was to investigate the effectiveness of extract of OB on rat behavior in the EPM test. Materials and Methods: Male Wistar...
متن کاملanxiolytic effect of ocimum basilicum extract in rats tested by elevated plus-maze task
conclusions our results demonstrated that the extract of ob could induce anxiolytic effect in rats after 1 week oral administration. the effect of ob was not induced through changes in motor activity. further investigations are necessary for pharmacological providing of ob and better understanding of its anxiolytic properties and neurobiological mechanisms. results the results showed that after...
متن کاملAnxiolytic-like effects of olanzapine, risperidone and fluoxetine in the elevated plus-maze test in rats.
In the present study was examined the effect of treatment with olanzapine or risperidone, given separately or in combination with fluoxetine, in the elevated plus-maze test (an animal model of anxiety) in male Wistar rats. The obtained results showed that treatment with olanzapine (1 mg/kg), risperidone (0.1 and 0.3 mg/kg) or fluoxetine (5 and 10 mg/kg) induced an anxiolytic-like effect in the ...
متن کاملThe effect of nobiletin on performance of rats in forced swimming and elevated plus maze tests in intranigral lipopolysaccharide rat model of Parkinson's disease
Background and Objective: Anti-inflammatory property of nobiletin (NOB) is proven and neuroinflammation is involved in triggering and progression of neurodegenerative disorder such as Parkinson's disease (PD). PD is a neurodegenerative disorder characterized by motor and non-motor features including psychiatric symptoms such as depression and anxiety. The purpose of this study to investigate wh...
متن کاملMyristic Acid Produces Anxiolytic-Like Effects in Wistar Rats in the Elevated Plus Maze
A mixture of eight fatty acids (linoleic, palmitic, stearic, myristic, elaidic, lauric, oleic, and palmitoleic acids) at similar concentrations identified in human amniotic fluid produces anxiolytic-like effects comparable to diazepam in Wistar rats. However, individual effects of each fatty acid remain unexplored. In Wistar rats, we evaluated the separate action of each fatty acid at the corre...
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ژورنال
عنوان ژورنال: European Journal of Pharmacology
سال: 2012
ISSN: 0014-2999
DOI: 10.1016/j.ejphar.2012.03.038